Edward T. Peltzer did his PhD research studying organic compounds found in meteorites. He was hoping to find clues to the origin of life on earth. In the video below Peltzer explains why life could not have arisen by natural means.
In the video, Edward Peltzer explains that when biomolecules such as amino acids and sugars are produced naturally, they are intermediates in a multi-step reaction and are consumed as quickly as they are produced. That reaction does not produce the biopolymers needed for life such as proteins or nucleic acids, instead the reaction produces tar.
Biopolymers cannot be produced naturally because without the cellular structures that compartmentalize biomolecules and control how they interact, the subunits will not form biopolymers, they will react randomly and form gunk. Even if by chance several subunits do form a biopolymer, that polymer is still going to go on to form gunk.
In the video, Peltzer discusses various origin of life theories including "protein first", "protein and nucleotides together", metabolism first, membranes first, clay, and RNA world and panspermia. None of these can explain how life could originate. Proteins do not polymerize naturally, they form gunk. This is why cataracts form in lens of the eye. The same is true for nucleotides. If one hypothesizes membranes formed spontaneously to protect biomolecules from the environment, then the reactants of polymerization will be used up without any means of replenishment. If the membranes are leaky, then you have the same problems as with no membrane at all. If you mix biomolecules with clay, they stick to the clay and stay there, they are removed from solution and cannot carry out any biological functions. Panspermia, the theory that life came to earth from space, doesn't solve anything unless the laws of chemistry are different elsewhere in the universe.
Peltzer concludes you can't produce a cell unless you already have a cell.